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I ordered a ultra duster to dust off the fan in my ps41tb is it safe to use it on the top I took off were the paste is it now has dust in it if I cant use the ultra duster canned air on it what can I use I dont want to replace the thermal paste
You can use canned air, a toothbrush, a vacuum, etc. You can use most anything to clean the fan. From your question though, it sounds like you removed the motherboard? If so you need to replace the thermal paste.
